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Testosterone is responsible for the development of male tissues such as the testes and prostate, as well as secondary sexual characteristics like facial and body hair, deep voice, and muscle mass

24 male Wistar rats, weighing between 170190 grams and eight weeks old, were obtained from Mansour Scientific Foundation (MSF) in Jeddah, KSA

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TNF was also shown to induce human OL progenitor cells to undergo death by pyroptosis, a pro-inflammatory programmed cell death mediated by inflammasome complex activation 55

Quantitative assessment of primary skin irritants in vitro in a cytotoxicity model: comparison with in vivo human irritation tests